Maturation of whisky delayed ethanol metabolism to lower the level of blood acetaldehyde and acetate with increasing inhibition of liver ADH activity by nonvolatile congeners. It also prolonged drunkenness by enhancing the neurodepressive effects of ethanol, due to increases in the amount of nonvolatile congeners. These biomedical effects of whisky maturation may reduce aversive reactions and cytotoxicity due to acetaldehyde, and may also limit overdrinking with the larger neurodepression.Another way to read this, I guess, is you get what you pay for, and if you pay for 20 year-old single malt whisky, you get less acetaldehyde -- which, on the whole, is not a bad deal.
(Link to article via @TheWhiskyGuy.)
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